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hnps-PLA Inhibitor

CAS No. 185298-58-2

hnps-PLA Inhibitor( hnps-PLA Inhibitor | MDK-8582 | MDK 8582 )

Catalog No. M17396 CAS No. 185298-58-2

Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    hnps-PLA Inhibitor
  • Note
    Research use only, not for human use.
  • Brief Description
    Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
  • Description
    MDK-8582, also known as Hnps-PLA Inhibitor, is an nhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). The best one inhibited hnps-PLA(2) and LTA(4)H-h with IC(50) values of 9.2 ± 0.5 μM and 2.4 ± 1.4 μM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    hnps-PLA Inhibitor | MDK-8582 | MDK 8582
  • Pathway
    Angiogenesis
  • Target
    FGFR
  • Recptor
    LTA(4)H-h| hnsPLA2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    185298-58-2
  • Formula Weight
    379.42
  • Molecular Formula
    C21H21N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N)C(=O)c1c(CC)n(Cc2ccccc2)c2c1c(OCC(=O)N)ccc2
  • Chemical Name
    2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meng H, Liu Y, Zhai Y, Lai L. Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase. Eur J Med Chem. 2013 Jan;59:160-7
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